Synergy of antimicrobial peptides and bacteria from frog skin

In the fight to protect frogs from chytrid fungus, there has been some speculation that different species of inhibitory bacteria may have a synergistic inhibitory effect on Bd. This means that because these bacteria are naturally found in communities on amphibian skin rather than in isolation, they might work together to protect frogs from being infected by the chytrid fungus. Some researchers recently found that using antimicrobial peptides isolated from the skin of the Mountain Yellow-Legged Frog (Rana muscosa) along with metabolites from a species of Pseudomonas bacteria commonly found on amphibian skin resulted in increased inhibition of Bd. This suggests that in addition to potential synergistic effects of skin bacteria, frog skin peptides can also work in association with their bacteria to prevent chytrid infection.

Frog: 6, Fungus: 7

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